Image Mike Wehr
Michael Wehr
Ph.D., Caltech
B.S., Brown University

Research Interests

We study how local circuits in the cerebral cortex encode and transform sensory information. We use mouse auditory cortex as a model system to investigate how cellular and network properties shape cortical responses to a continuous and temporally complex stream of sensory data.

Research in the Wehr Lab combines aspects of cellular, systems, and computational neuroscience, by using the tools of molecular biology and cellular physiology to address systems-level questions. Using a variety of approaches, including in vivo whole cell recordings, high-density electrophysiology in behaving animals, mesoscopic 2-photon imaging, optogenetics, quantitative behavior, and computational modeling, we are trying to identify the cellular, synaptic, and network mechanisms with which cortical circuits process auditory information, leading ultimately to our perceptual experiences of acoustic streams, such as music and speech.

Lab Members

Clifford Keller
Sam Mehan
Graduate Student
Matt Nardoci
Graduate Student
Luke Ott
Research Staff
Molly Shallow
Graduate Student
Michael Wehr
Aldis Weible
Research Staff


Santiago Jaramillo
Auditory cognition, behavioral flexibility and predictive processing
Luca Mazzucato
Computational neuroscience, Artificial Intelligence
David McCormick
Cortical neural circuits of behavior and attention
Cristopher Niell
Neural circuits for natural vision
Matt Smear
Active Olfaction
Philip Washbourne
Developmental neuroscience with a focus on social behavioral circuits