ION Seminar Series

For the 2020-2021 academic year, ION seminars are held remotely at either 12 PM or 4 PM PT on Thursdays unless otherwise specified.  Seminars are hosted on Zoom and are open to the UO community and occasionally on World Wide Neuro.  Links to the weekly seminar will be advertised through the ION mailing list and those not on the list can request access by contacting Jenna Penny at seminars @ uoneuro.uoregon.edu. For more information and support for using the Zoom platform visit UOregon Zoom.

 

Upcoming Institute of Neuroscience Seminar

Xiaoxuan Jia, PhD

Senior Scientist
Allen Institute

"Tracking information flow in mouse visual areas"

Host: Luca Mazzucato

Thursday, April 15th, 2021 at 12 PM PDT

Zoom access provided via ION mailing list

The anatomy of the mouse visual system indicates it is organized hierarchically, yet direct functional evidence is still lacking. Here, we simultaneously recorded spiking activity from tens of thousands of neurons from six cortical and two thalamic regions along the anatomically defined visual hierarchy in awake mice. Using cross-correlation analysis, we reveal that the organization of inter-area functional connectivity during visual stimulation mirrors the anatomical hierarchy. We find that four classical hierarchical measures —response latency, receptive field size, receptive field complexity, and response decay timescale—are all correlated with the hierarchy. Moreover, recordings during a visual change-detection task reveal that the correlation between neural activity and behavioral choice increases along the hierarchy. These results suggest a functional hierarchy that follows anatomy during sensory drive, which forms the first principle of functional organization in mouse visual system. However, since there are extensive recurrent connections between areas, the signal flow is not a simple one-way pass along the hierarchy. We generated multi-area, directed graphs with single-neuron resolution by analyzing millisecond-timescale leading and lagging spike-timing relationships between pairs of neurons. Network analysis revealed two spatially-distributed functional modules. These modules differ in their layer and area distributions, network properties, individual and population-level temporal dynamics, suggesting they mediate different stages of sensory processing. One module is positioned to transmit feedforward sensory signals along the hierarchy, while the other receives convergent input and engages in recurrent processing. These results reveal a cellular-resolution cortical network topology with distinct sensory processing modules mediating feedforward and recurrent processes, which forms the second principle of functional organization in mouse visual areas.

Learn More

 

Spring 2021

DATE SPEAKER TITLE HOST

4/1/2021
12 PM PT

Bernado Sabatini Circuits of action selection and reinforcement Denver Ncube
4/8/2021
4 PM PT
Nicoladie Tam How to speed up the brain, how emotions bias decisions, is ignorance bliss, is love priceless, gender-difference in emotional sensitivity, and decode movement directions by applying computational theories and analyses of cortical optical imaging hemodynamic signals Kelsey Schultz
4/15/2021
12 PM PT
Xiaoxuan Jia Tracking information flow in mouse visual areas Luca Mazzucato
4/22/2021
12 PM PT
Fanny Cazettes Multiplexed accumulation of evidence in the mouse frontal cortex Luca Mazzucato
4/29/2021 Michael Granato TBA Sarah Ackerman & Judith Eisen
5/6/2021 
12 PM PT
Marla Feller Wiring up direction selective circuits in the retina Adam Miller
5/13/2021
12 PM PT
Gerry Downes From swimming to seizures: Investigating locomotor behavior and epilepsy in developing zebrafish Anne Martin
5/20/2021  Kang Shen TBA Sarah Ackerman
5/27/2021 Patrick Kanold TBA Santiago Jaramillo
6/3/2021 SueYeon Chung TBA Luca Mazzucato
6/10/2021 Marta Zlatic CSN Fest - Finals Week Emily Heckman

Fall 2020

DATE SPEAKER TITLE HOST
10/22/2020
Noon PT
Eve Marder Mind-Brain Institute of Neurosicence Lecture:  "Differential Resilience to Pertubations of Circuits with Similar Performance David McCormick
10/29/2020
12 PM PT
Cody Smith Glial and Neuronal Interactions that Build the Nervous System Judith Eisen
11/5/2020
12 PM PT
Georg Keller Cortical circuits for predictive processing David McCormick
11/12/2020
12 PM PT
Phyllis Robinson Best Practices in Cultivating Success for Underrepresented Populations Pursuing Degrees in Stem in Higher Education Judith Eisen
DEI
11/19/2020 
12 PM PT
David McLean Decoding neural circuits for movement control by studying zebrafish James Murray
11/26/2020   No Seminar - Thanksgiving Holiday  
12/3/2020
12 PM PT
Vanessa Ruta Theme and Variations: Circuit Mechanisms of Behavioral Evolution Emily Heckman
Womxn in Neuroscience
12/10/2020   No Seminar - Finals Week  

Winter 2021

DATE SPEAKER TITLE HOST
1/14/2021
4 PM PT
Matthieu Louis Neural computations directing orientation behavior during larval chemotaxis Matt Smear
1/21/2021
Postponed
Sonja Hofer Postponed David McCormick
1/28/2021
12 PM PT
Amy Orsborn Measuring, modeling and shaping neural plasticity in brain-machine interfaces James Murray
2/4/2021   No Seminar - Graduate Recruitment  
2/11/2021
12 PM PT
Sheena Josselyn Making memories in mice Dasa Zeithamova
2/18/2021 
Postponed
Caleb Kemere Postponed: Latent Spaces of Memory in Real and Virtual Worlds Cris Niell
2/25/2021
12 PM PT
Maria Geffen The role of cortical adaptation and plasticity in auditory learning and behavior Isabella Salinas
Womxn in Neuroscience
Wednesday
3/3/2021
10 AM PT
Kaela Singleton Control of Neuron Formation in Neurodevelopmental & Neurodegernative Disorders
Womxn in Neuroscience hosted seminar
Rachel Lukowicz
 
3/4/2021
4 PM PT
Melissa Warden Neuromodulation and the balance between goal-directed and reactive behavior Emily Sylwestrak
3/11/2021
12 PM PT
Richard Mooney From Song to Synapse Santiago Jaramillo
3/18/2021   No Seminar - Finals Week