Matt Smear

Assistant Professor, Department of Psychology
Member, ION

212a Huestis


Research Interests: Systems Neuroscience

Overview: Dr. Smear studies the neural mechanisms of olfactory function in mice. Mice have an excellent sense of smell – much of their genome encodes odorant receptors (over 1000 genes), and a large portion of their brain processes olfactory information. These neural features support a rich repertoire of olfactory behaviors. The Smear lab interrogates olfactory function with a battery of psychophysical tests, while manipulating and recording neuronal activity with genetics, electrophysiology, and imaging. From these studies, the lab will pursue general principles of how neural circuits generate behavior.


Related Articles

Algorithms for Olfactory Search across Species.

J Neurosci. 2018 Oct 31;38(44):9383-9389

Authors: Baker KL, Dickinson M, Findley TM, Gire DH, Louis M, Suver MP, Verhagen JV, Nagel KI, Smear MC

Localizing the sources of stimuli is essential. Most organisms cannot eat, mate, or escape without knowing where the relevant stimuli originate. For many, if not most, animals, olfaction plays an essential role in search. While microorganismal chemotaxis is relatively well understood, in larger animals the algorithms and mechanisms of olfactory search remain mysterious. In this symposium, we will present recent advances in our understanding of olfactory search in flies and rodents. Despite their different sizes and behaviors, both species must solve similar problems, including meeting the challenges of turbulent airflow, sampling the environment to optimize olfactory information, and incorporating odor information into broader navigational systems.

PMID: 30381430 [PubMed - in process]